Fluorescent agents in the biolab.

Fluorescence Imaging at the Angström Scale

MPSP Lecture by Prof. Steffen Sahl (Göttingen)
Fluorescent agents in the biolab.
Image: Jan-Peter Kasper (University of Jena)
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Lecture
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English
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Abstract

The lecture will describe the initial demonstrations of quantitative intra-molecular distance measurement capabilities with MINFLUX fluorescence nanoscopy, in the FRET (Förster resonance energy transfer) range and below, down to Angström distances. MINFLUX localization, pioneered and developed by Stefan Hell and his laboratory, achieves unique measurement precisions of single molecules.

Research interests of the lecturer

Dr. Steffen J. Sahl researches at the Max Planck Institute for Multidisciplinary Sciences in Göttingen. His research interests are in biophysical imaging and spectroscopy at high resolution and sensitivity, in particular the further development of super-resolved fluorescence microscopy (nanoscopy), and applying these methods to analyze the intracellular pathogenic events involving aggregation-prone proteins and their fragments in neurodegenerative disorders, notably Huntington's and prion diseases.